Infectious Diseases

NYBC 576: Methods for the Diagnosis, Detection and Treatment of Babesiosis. (C. Lobo, E. Montero). A protein important in the invasion of RBCs by Babesia spp is described. Methods for the detection of Babesia contamination in blood, diagnosis of Babesia infection in mammals and screening method for small molecule therapeutics is presented.

NYBC 571: A Method for the Prevention of HIV-1 Infection in Females. (A.Neurath, A. Stone, N. Strick). The formulation and method of use of a vaginal preparation to prevent HIV-1 infection is described.

NYBC 568: Method for the Treatment and Prevention of HIV-1 Infection by Small Helical Peptides. (A. Debnath). The patent describes a novel class of helical peptides with the ability to penetrate cells and to inhibit the assembly of capsid-containing viruses.

NYBC 556: Method for the Detection and Treatment of Severe Acute Respiratory Syndrome-Associated Coronavirus (SARS-CoV). (S. Jiang, Y. He). The patent describes a monoclonal antibody specific for the receptor-binding domain (RBD) of the spike protein of the SARS-associated Coronavirus. Uses of the antibody include methods for the diagnosis of SARS and for screening of compounds to treat SARS.